Vitamin D vs Rhodiola

for mood

Stronger evidence: Vitamin D

Stronger effect: Vitamin D

Safety: Rhodiola has the more serious interaction profile (minor vs uncertain).

For mood, Vitamin D has the stronger evidence grade.

Vitamin D

grade C low certainty

small mood benefit, mostly in people who are deficient

Rhodiola

studied, no effect moderate certainty

Not recommended for mood disorders

sources: PMID:00000005 · PMID:35311615