How does dietary nitrate relate to blood pressure?
Short answer
In this review, higher dietary nitrate doses were associated with lower systolic blood pressure. This does not predict an individual’s benefit.
- Who was studied
- Not encoded in this source record
- Compared with
- Dose changes against trial controls; placebo comparisons required for review eligibility. A common placebo composition is unknown.
- What was measured
- systolic blood pressure
- How long
- Acute, short-term and medium-term source windows; see verified timing definitions below.
This describes the people and conditions studied. It does not say whether the result applies to you.
Study timing and comparison context
Verified factual observations from the publisher’s methods. The extracted estimates still await human review.
- Acute
- Within a few hours
- Short-term
- 1–7 days
- Medium-term
- More than 7 days
Duration definitions: Statistical analysis. These definitions do not assign a duration to a result whose window is unspecified, or rank the windows.
Review eligibility: comparisons with placebo were required (Eligibility criteria). This does not establish a common placebo formulation or identify every trial’s actual control.
Dose-response method: dose changes were assessed against trial controls (Statistical analysis); this describes the analysis method, not a single shared comparator.
Separate plasma-marker assessment: chronic assessment means several days (Statistical analysis). This is not the medium-term estimate window.
This context record does not resolve population, baseline, a common placebo composition, or unspecified result windows.
Publisher methods · DOI 10.1186/s12937-025-01114-8 · Context version 1. Verified factual observations; the full publisher document was not retained. Recorded publisher license: CC BY-NC-ND 4.0.
What the source found
Show data table
| Comparison | Estimate | 95% confidence interval | Unit |
|---|---|---|---|
| acute | −0.28 | −0.40 to −0.17 | mmHg |
| short-term | −0.24 | −0.40 to −0.07 | mmHg |
| medium-term | −0.48 | −0.71 to −0.25 | mmHg |
- Unit
- WMD in mmHg per 1 mmol dietary nitrate
- Who & when
- Source-labelled windows are not independent comparisons or a time course. Review-wide counts are not per-estimate sample sizes.
- Source
- PMID 40128734 · paper version 4