Research library

Versioned snapshot of this displayed record. It may no longer be current; audio requires a successful current-version check.

PMID 38745424: PSQI Stable finding ID: finding:pmid:38745424:psqi:between-condition. Finding version: 1. Revision: finding:pmid:38745424:psqi:between-condition:v1. Content hash: sha256:872d83da20f0b695fbae17cba7d48cf4cfb9a1ae9cd6542c9a43b7b753802fcd. Paper version: 2. Paper content hash: sha256:08de6964245b14f063c6e5be09c444866724662db48f96d21e63b9c375a1714d. AI-extracted — pending human review Extraction status: machine extracted. Source status is not human clinical review. Publication status: published. Record review status: not reviewed. Not poolable: one source-reported result, not a pooled treatment estimate. Authors reported a direction only for sleep quality (PSQI): favours the studied intervention. Studied combination: 1.9 mg melatonin + 200 mg elemental magnesium. Studied route/context: unclear. otherwise healthy individuals with sleep disturbances; double-blinded, randomized, crossover trial. supplement condition versus placebo. sleep quality (PSQI) at 4 week intervention. Participants / population: otherwise healthy individuals with sleep disturbances. Study design: double-blinded, randomized, crossover trial. Studied intervention: supplement condition. Studied combination: 1.9 mg melatonin + 200 mg elemental magnesium. Studied route / context: unclear. Comparator: placebo. Measured outcome: sleep quality (PSQI). Timepoint: 4 week intervention. Source-reported direction: favours the studied intervention. Direction only; no numerical magnitude is available in this record. Reported p < 0.05. No between-arm contrast, interval estimate or pooled result is calculated here; the values above are exactly as the source reported them. Reported limitation: AI-extracted; pending human review. Reported limitation: A combined melatonin-magnesium intervention; no isolated ingredient effect is established. Reported limitation: Crossover results lack a supported magnitude or paired uncertainty in the accepted source. Reported limitation: Average PSQI scores still indicated poor sleep quality in both conditions. Finding revision: finding:pmid:38745424:psqi:between-condition:v1. Finding version: 1. Finding content hash: sha256:872d83da20f0b695fbae17cba7d48cf4cfb9a1ae9cd6542c9a43b7b753802fcd. Paper version: 2. Paper version content hash: sha256:08de6964245b14f063c6e5be09c444866724662db48f96d21e63b9c375a1714d. Source content hash: sha256:7eb923eead09c74399772ed1392e693e2b2a9840938e04e47436e0bd9d4836f9. Extraction policy: reported-findings-initial2-v1. Extraction policy hash: sha256:c0d84a3eafb1f7e7f5c4931e65dc3d9d9301f05110e8db8b8718d2b734ec5563. Extraction method version: source-grounded-reported-findings-v1. Field locators: reportedDirection → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; reportedSignificance.value → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.population → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.experimentalIntervention → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.experimentalInterventionComponents → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.comparator → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.design → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.outcomeConstruct → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.instrument → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result; applicability.participantMetric → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text: Abstract; authors-reported result. Source document: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=38745424&rettype=abstract&retmode=text. Source hash: sha256:7eb923eead09c74399772ed1392e693e2b2a9840938e04e47436e0bd9d4836f9. Locators: reportedDirection: Abstract; authors-reported result; reportedSignificance.value: Abstract; authors-reported result; applicability.population: Abstract; authors-reported result; applicability.experimentalIntervention: Abstract; authors-reported result; applicability.experimentalInterventionComponents: Abstract; authors-reported result; applicability.comparator: Abstract; authors-reported result; applicability.design: Abstract; authors-reported result; applicability.outcomeConstruct: Abstract; authors-reported result; applicability.instrument: Abstract; authors-reported result; applicability.participantMetric: Abstract; authors-reported result; timepoint: Abstract; intervention duration; association-combination: Abstract; combined intervention; association-combination: Abstract; combined intervention; association-combination: Abstract; combined intervention; association-outcome: Abstract; authors-reported result. Canonical paper: /studies/38745424. This is a reading of this version, not a clinical recommendation. Check the current paper page for updates.

Versioned snapshot of this displayed record. It may no longer be current; audio requires a successful current-version check.

PMID 39138397: ISI Stable finding ID: finding:pmid:39138397:isi:postoperative-two-weeks. Finding version: 1. Revision: finding:pmid:39138397:isi:postoperative-two-weeks:v1. Content hash: sha256:38d9f5892c47e85982a8771ac7f604220ea728aa033ee0d13bf28c62dac2257b. Paper version: 2. Paper content hash: sha256:dd3bc7bade8b84173b4ecfbb47525a9c6860c70bd9a0d4767e15c904a9cb201c. AI-extracted — pending human review Extraction status: machine extracted. Source status is not human clinical review. Publication status: published. Record review status: not reviewed. Not poolable: one source-reported result, not a pooled treatment estimate. Authors reported insomnia severity (ISI) as Mg sulphate group 17.45 score and Control group 22.4 score, each summarised separately. Studied route/context: intravenous. patients undergoing lumbar fixation; randomized controlled trial. Magnesium sulphate versus general anesthesia. insomnia severity (ISI) at 2 weeks after surgery. Participants / population: patients undergoing lumbar fixation. Study design: randomized controlled trial. Studied intervention: Magnesium sulphate. Studied combination: not reported. Studied route / context: intravenous. Comparator: general anesthesia. Measured outcome: insomnia severity (ISI). Timepoint: 2 weeks after surgery. Mg sulphate group: reported value 17.45 score; SD 4.32; participants 40. Control group: reported value 22.4 score; SD 3.29; participants 40. Reported p < 0.001. No between-arm contrast, interval estimate or pooled result is calculated here; the values above are exactly as the source reported them. Reported limitation: AI-extracted; pending human review. Reported limitation: Lumbar-fixation surgery and intraoperative magnesium sulphate adjunct to general anaesthesia; not oral supplementation. Reported limitation: Raw arm summaries at two weeks after surgery; not change scores or the adjusted regression coefficient. Reported limitation: Analysis-population and adjustment details are not established by this descriptive extraction; no pooled effect or certainty upgrade. Finding revision: finding:pmid:39138397:isi:postoperative-two-weeks:v1. Finding version: 1. Finding content hash: sha256:38d9f5892c47e85982a8771ac7f604220ea728aa033ee0d13bf28c62dac2257b. Paper version: 2. Paper version content hash: sha256:dd3bc7bade8b84173b4ecfbb47525a9c6860c70bd9a0d4767e15c904a9cb201c. Source content hash: sha256:7a50003b05a8c9c02f3dd5dd52359b0e278f4c8efa0b850d02ba8da68ee45a92. Extraction policy: reported-findings-initial2-v1. Extraction policy hash: sha256:c0d84a3eafb1f7e7f5c4931e65dc3d9d9301f05110e8db8b8718d2b734ec5563. Extraction method version: source-grounded-reported-findings-v1. Field locators: applicability.population → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Abstract; authors-reported result; applicability.experimentalIntervention → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Abstract; authors-reported result; applicability.experimentalInterventionRoute → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Abstract; authors-reported result; applicability.comparator → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Abstract; authors-reported result; applicability.design → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Abstract; authors-reported result; applicability.instrument → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Abstract; authors-reported result; applicability.outcomeConstruct → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Abstract; authors-reported result; applicability.participantMetric → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; postoperative ISI; experimental.armLabel → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; column header; comparator.armLabel → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; column header; experimental.n → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; experimental column n; comparator.n → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; control column n; experimental.mean → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; ISI; experimental mean; experimental.dispersion.value → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; ISI; experimental SD; comparator.mean → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; ISI; control mean; comparator.dispersion.value → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; ISI; control SD; experimental.unit → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Methods; ISI scale; comparator.unit → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Methods; ISI scale; reportedSignificance.value → https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/: Table 2; ISI; p-value. Source document: https://pmc.ncbi.nlm.nih.gov/articles/PMC11320981/. Source hash: sha256:7a50003b05a8c9c02f3dd5dd52359b0e278f4c8efa0b850d02ba8da68ee45a92. Locators: applicability.population: Abstract; authors-reported result; applicability.experimentalIntervention: Abstract; authors-reported result; applicability.experimentalInterventionRoute: Abstract; authors-reported result; applicability.comparator: Abstract; authors-reported result; applicability.design: Abstract; authors-reported result; applicability.instrument: Abstract; authors-reported result; applicability.outcomeConstruct: Abstract; authors-reported result; applicability.participantMetric: Table 2; postoperative ISI; experimental.armLabel: Table 2; column header; comparator.armLabel: Table 2; column header; experimental.n: Table 2; experimental column n; comparator.n: Table 2; control column n; experimental.mean: Table 2; ISI; experimental mean; experimental.dispersion.value: Table 2; ISI; experimental SD; comparator.mean: Table 2; ISI; control mean; comparator.dispersion.value: Table 2; ISI; control SD; experimental.unit: Methods; ISI scale; comparator.unit: Methods; ISI scale; reportedSignificance.value: Table 2; ISI; p-value; timepoint: Methods; ISI assessment time; association-intervention: Abstract; authors-reported result; association-outcome: Abstract; authors-reported result. Canonical paper: /studies/39138397. This is a reading of this version, not a clinical recommendation. Check the current paper page for updates.