We don't sell supplements. We never will.

Substrate (evidencebased.info) is an independently reviewed evidence-answer system that translates clinical research into graded, claim-level answers about benefits, harms, doses, interactions and uncertainty — with no product sales and no affiliate revenue.

The one sentence

Substrate sells no supplements, takes no affiliate commissions, accepts no supplement advertising, and receives no money from any supplement company. When the evidence says something doesn't work, saying so costs us nothing.

How we make money

Precisely, and updated annually:

Revenue-by-source percentages publish here once billing volume is material enough that a single-quarter number would not be misleading on its own.

How we don't

The editorial firewall

Commercial staff cannot see, influence, or veto a grade. Reviewers can refuse to sign and can publicly dissent. Substrate cannot overrule a reviewer's refusal. This is written into every reviewer agreement, not held as an unwritten norm.

Reviewer conflicts of interest

Every reviewer discloses, annually and per review, using the ICMJE disclosure format — grants, consulting fees, honoraria, patents, equity, board positions, and non-financial interests (a strongly held public position on an intervention is a disclosable interest, same as money). See reviewer profiles for individual disclosures.

Recusal rules: a reviewer with a material financial interest in an intervention cannot sign claims about it. A reviewer with a strong prior public position on it can sign only alongside a second, independent reviewer. Both rules are enforced in the publish pipeline (credential-to-claim matching, CLAIM-SCHEMA §11), not by memory.

The gift, sample & hospitality policy

Gift/sample log: no entries — nothing received. This section updates the moment that changes.

What would compromise us

Revenue pressure meeting an unpopular grade is the actual risk, not a hypothetical one. If a low grade ever cost us a subscriber, a partnership, or press goodwill, the response is documented here, not smoothed over. The guardrail is structural — no product money to lose — not a promise we're asking to be trusted on.

Committed in advance

If this happensWe commit to
An investor acquires a supplement-industry holdingDisclosed within 30 days; investor recused from all product decisions; if material, published with an exit offer
A supplement company offers a licensing dealTerms published. Data licensing is fine; influence over a grade is not, at any price
A brand threatens legal action over a low gradeThe threat is published
A reviewer takes industry consulting workDisclosed; recused from affected claims; disclosed retroactively on every claim they previously signed
Revenue pressure meets an unpopular gradeThe grade doesn't move. The incident is documented in the corrections/accuracy record

How to hold us to it

Report an error · Corrections log · Public metrics · URAC self-audit. Audit us against any of this — we mean it.

Preferred sources

Google lets you elect the sources you want to see more of in search — it's called "preferred sources." If you find our grades useful, you can tell Google to show you more of them from your search settings. We're mentioning this once, here — we won't nag you about it in the product or the newsletter.