Vitamin D vs N-Acetylcysteine

for mood

Stronger evidence: tie

Stronger effect: Vitamin D

Safety: Vitamin D carries a minor interaction; N-Acetylcysteine has none recorded.

For mood, the two are evidence-matched; the difference is in effect and safety.

grade C low certainty

small mood benefit, mostly in people who are deficient

grade C low certainty

preliminary evidence as an adjunct in some psychiatric conditions; not established as a standalone

1200–2400 mg/day, adults

sources: PMID:00000005 · PMID:10000012