PMID 39498904: Computerized Mental Performance Assessment System (COMPASS)
- AI-extracted — pending human review
- Extraction status: machine extracted. Source status is not human clinical review.
- Publication status: published. Record review status: not reviewed.
- Not poolable: one source-reported result, not a pooled treatment estimate.
Authors reported a direction only for episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)): favours the studied intervention.
Reported p < 0.05.
- Studied route/context: orally.
adults with self-reported cognitive and energy problems; prospective, randomized, placebo-controlled study. Ashwagandha (Withania somnifera) root extract (ARE) 600 mg/day versus identical placebo. episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)) at 8 week baseline.
That’s the gist — a fine place to stop. This describes the studied groups, not personal suitability.
Understand the result
Direction only. No numerical magnitude or uncertainty range is recorded for this finding.
- Who & when
- adults with self-reported cognitive and energy problems; prospective, randomized, placebo-controlled study. Ashwagandha (Withania somnifera) root extract (ARE) 600 mg/day versus identical placebo. episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)) at 8 week baseline.
- Source
- PMID 39498904 · finding version 2
No between-arm contrast, interval estimate or pooled result is calculated here; the values above are exactly as the source reported them.
Same finding version 2; paper version 3. Exact identity, status and limitations remain in this article.
Source-reported direction
Source-reported direction: favours the studied intervention.
No between-arm contrast, interval estimate or pooled result is calculated here; the values above are exactly as the source reported them.
Studied context
| Participants / population | adults with self-reported cognitive and energy problems |
|---|---|
| Study design | prospective, randomized, placebo-controlled study |
| Analysis population | unclear |
| Covariate adjustment | Adjustment unresolved in this record |
| Studied intervention | Ashwagandha (Withania somnifera) root extract (ARE) 600 mg/day |
| Studied route / context | orally |
| Comparator | identical placebo |
| Measured outcome | episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)) |
| Timepoint | 8 week baseline |
Limitations reported for this finding
- One generalized p<.05 statement covers the listed three COMPASS items; no item-specific significance, effect sizes, confidence intervals, or exact p-values are given.
- Other outcomes with baseline changes and reported safety are retained in inventory; the abstract does not clearly state between-group inferential comparisons for those outcomes.
- The abstract describes participants as healthy subjects aged 30–75 years and separately as adults with self-reported cognitive and energy problems; the population field anchors the latter, and both descriptions are retained.
- Authors report greater improvement from baseline with ARE versus placebo across the three COMPASS items, with one generalized p<0.05 statement for the bundle; do not assign significance separately to each item.
You can stop here, or inspect the evidence and its original sources.
adults with self-reported cognitive and energy problems; prospective, randomized, placebo-controlled study. Ashwagandha (Withania somnifera) root extract (ARE) 600 mg/day versus identical placebo. episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)) at 8 week baseline.
Source and extraction detail
- Finding revision
- finding:examine2025:39498904:1:v2
- Finding version
- 2
- Finding content hash
- sha256:6a0e3fef7184bca77a0b877d1413ab53339e1cc8b14fa3444a90edd657f9def5
- Paper version
- 3
- Paper version content hash
- sha256:ec8bb69480bfe47eebdd69054aed9ba008f5f0094b77c290b5e44e542554b410
- Source content hash
- sha256:4a7d7a515cd2be4b73df686d82b0b12d4eef89b1a89e67a5bfad5724779bc69b
- Extraction policy
- context164-source-topic-policy:a2ed0afcca38b97b057564d0e64bc4e30a5030cfe7c3f08c9ff6a3b499a0aac9
- Extraction policy hash
- sha256:a2ed0afcca38b97b057564d0e64bc4e30a5030cfe7c3f08c9ff6a3b499a0aac9
- Extraction method version
- source-anchored-qualitative-context/v1
- Field locators
- applicability.population → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, route/duration; applicability.comparator → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.design → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, design; applicability.instrument → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, instrument; applicability.outcomeConstruct → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.participantMetric → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; reportedDirection → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; limitations → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; reportedSignificance.value → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, bundled significance result
Source documents
- https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text — sha256:4a7d7a515cd2be4b73df686d82b0b12d4eef89b1a89e67a5bfad5724779bc69b (applicability.population → PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention → PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute → Abstract, route/duration; applicability.comparator → PubMed abstract, exact acquired sentence context; applicability.design → Abstract, design; applicability.instrument → Abstract, instrument; applicability.outcomeConstruct → PubMed abstract, exact acquired sentence context; applicability.participantMetric → PubMed abstract, exact acquired sentence context; reportedDirection → PubMed abstract, exact acquired sentence context; limitations → PubMed abstract, exact acquired sentence context; reportedSignificance.value → Abstract, bundled significance result; applicability.population → PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention → PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute → Abstract, route/duration; applicability.comparator → PubMed abstract, exact acquired sentence context; applicability.design → Abstract, design; applicability.instrument → Abstract, instrument; applicability.outcomeConstruct → PubMed abstract, exact acquired sentence context; applicability.participantMetric → PubMed abstract, exact acquired sentence context; reportedDirection → PubMed abstract, exact acquired sentence context; limitations → PubMed abstract, exact acquired sentence context; reportedSignificance.value → Abstract, bundled significance result; applicability.population → PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention → PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute → Abstract, route/duration; applicability.comparator → PubMed abstract, exact acquired sentence context; applicability.design → Abstract, design; applicability.instrument → Abstract, instrument; applicability.outcomeConstruct → PubMed abstract, exact acquired sentence context; applicability.participantMetric → PubMed abstract, exact acquired sentence context; reportedDirection → PubMed abstract, exact acquired sentence context; limitations → PubMed abstract, exact acquired sentence context; reportedSignificance.value → Abstract, bundled significance result; applicability.timepoint → Abstract, baseline/week-8 assessment)
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PMID 39498904: Computerized Mental Performance Assessment System (COMPASS) Stable finding ID: finding:examine2025:39498904:1. Finding version: 2. Revision: finding:examine2025:39498904:1:v2. Content hash: sha256:6a0e3fef7184bca77a0b877d1413ab53339e1cc8b14fa3444a90edd657f9def5. Paper version: 3. Paper content hash: sha256:ec8bb69480bfe47eebdd69054aed9ba008f5f0094b77c290b5e44e542554b410. AI-extracted — pending human review Extraction status: machine extracted. Source status is not human clinical review. Publication status: published. Record review status: not reviewed. Not poolable: one source-reported result, not a pooled treatment estimate. Authors reported a direction only for episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)): favours the studied intervention. Studied route/context: orally. adults with self-reported cognitive and energy problems; prospective, randomized, placebo-controlled study. Ashwagandha (Withania somnifera) root extract (ARE) 600 mg/day versus identical placebo. episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)) at 8 week baseline. Participants / population: adults with self-reported cognitive and energy problems. Study design: prospective, randomized, placebo-controlled study. Analysis population: unclear. Covariate adjustment: Adjustment unresolved in this record. Studied intervention: Ashwagandha (Withania somnifera) root extract (ARE) 600 mg/day. Studied combination: Not encoded in this record. Studied route / context: orally. Comparator: identical placebo. Measured outcome: episodic memory, working memory, and accuracy of attention (Computerized Mental Performance Assessment System (COMPASS)). Timepoint: 8 week baseline. Source-reported direction: favours the studied intervention. Direction only; no numerical magnitude is available in this record. Reported p < 0.05. No between-arm contrast, interval estimate or pooled result is calculated here; the values above are exactly as the source reported them. Reported limitation: One generalized p<.05 statement covers the listed three COMPASS items; no item-specific significance, effect sizes, confidence intervals, or exact p-values are given. Reported limitation: Other outcomes with baseline changes and reported safety are retained in inventory; the abstract does not clearly state between-group inferential comparisons for those outcomes. Reported limitation: The abstract describes participants as healthy subjects aged 30–75 years and separately as adults with self-reported cognitive and energy problems; the population field anchors the latter, and both descriptions are retained. Reported limitation: Authors report greater improvement from baseline with ARE versus placebo across the three COMPASS items, with one generalized p<0.05 statement for the bundle; do not assign significance separately to each item. Finding revision: finding:examine2025:39498904:1:v2. Finding version: 2. Finding content hash: sha256:6a0e3fef7184bca77a0b877d1413ab53339e1cc8b14fa3444a90edd657f9def5. Paper version: 3. Paper version content hash: sha256:ec8bb69480bfe47eebdd69054aed9ba008f5f0094b77c290b5e44e542554b410. Source content hash: sha256:4a7d7a515cd2be4b73df686d82b0b12d4eef89b1a89e67a5bfad5724779bc69b. Extraction policy: context164-source-topic-policy:a2ed0afcca38b97b057564d0e64bc4e30a5030cfe7c3f08c9ff6a3b499a0aac9. Extraction policy hash: sha256:a2ed0afcca38b97b057564d0e64bc4e30a5030cfe7c3f08c9ff6a3b499a0aac9. Extraction method version: source-anchored-qualitative-context/v1. Field locators: applicability.population → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, route/duration; applicability.comparator → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.design → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, design; applicability.instrument → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, instrument; applicability.outcomeConstruct → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; applicability.participantMetric → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; reportedDirection → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; limitations → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: PubMed abstract, exact acquired sentence context; reportedSignificance.value → https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text: Abstract, bundled significance result. Source document: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=39498904&rettype=abstract&retmode=text. Source hash: sha256:4a7d7a515cd2be4b73df686d82b0b12d4eef89b1a89e67a5bfad5724779bc69b. Locators: applicability.population: PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention: PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute: Abstract, route/duration; applicability.comparator: PubMed abstract, exact acquired sentence context; applicability.design: Abstract, design; applicability.instrument: Abstract, instrument; applicability.outcomeConstruct: PubMed abstract, exact acquired sentence context; applicability.participantMetric: PubMed abstract, exact acquired sentence context; reportedDirection: PubMed abstract, exact acquired sentence context; limitations: PubMed abstract, exact acquired sentence context; reportedSignificance.value: Abstract, bundled significance result; applicability.population: PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention: PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute: Abstract, route/duration; applicability.comparator: PubMed abstract, exact acquired sentence context; applicability.design: Abstract, design; applicability.instrument: Abstract, instrument; applicability.outcomeConstruct: PubMed abstract, exact acquired sentence context; applicability.participantMetric: PubMed abstract, exact acquired sentence context; reportedDirection: PubMed abstract, exact acquired sentence context; limitations: PubMed abstract, exact acquired sentence context; reportedSignificance.value: Abstract, bundled significance result; applicability.population: PubMed abstract, exact acquired sentence context; applicability.experimentalIntervention: PubMed abstract, exact acquired sentence context; applicability.experimentalInterventionRoute: Abstract, route/duration; applicability.comparator: PubMed abstract, exact acquired sentence context; applicability.design: Abstract, design; applicability.instrument: Abstract, instrument; applicability.outcomeConstruct: PubMed abstract, exact acquired sentence context; applicability.participantMetric: PubMed abstract, exact acquired sentence context; reportedDirection: PubMed abstract, exact acquired sentence context; limitations: PubMed abstract, exact acquired sentence context; reportedSignificance.value: Abstract, bundled significance result; applicability.timepoint: Abstract, baseline/week-8 assessment. Canonical paper: /studies/39498904. This is a reading of this version, not a clinical recommendation. Check the current paper page for updates.
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