Omega-3 vs Turmeric
for mood
Stronger evidence: tie
Stronger effect: Omega-3
Safety: Omega-3 has the more serious interaction profile (serious vs moderate).
For mood, the two are evidence-matched; the difference is in effect and safety.
Omega-3
grade C moderate certainty
small benefit for depressive symptoms, clearest with higher-EPA formulations
1–2 g EPA, adults with depression
Turmeric
grade C low certainty
curcumin may reduce depressive symptoms as an adjunct; bioavailability-limited
500–1000 mg curcumin/day, adults with depression
sources: PMID:20000102 · PMID:42186284