Creatine vs Turmeric
for mood
Stronger evidence: tie
Stronger effect: tie
Safety: Turmeric carries a moderate interaction; Creatine has none recorded.
For mood, the two are evidence-matched; the difference is in effect and safety.
Creatine
grade C low certainty
emerging evidence as an adjunct for depressive symptoms; trials small
3–5 g/day, adults with depression
Turmeric
grade C low certainty
curcumin may reduce depressive symptoms as an adjunct; bioavailability-limited
500–1000 mg curcumin/day, adults with depression
sources: PMID:42180567 · PMID:42186284