Glycine: what the evidence actually shows

Reviewer and governance status are shown on each atomic claim below.

What it is

Glycine is tracked as a health intervention in this evidence graph. No additional aliases are recorded.

Studied forms and doses

No form-specific catalog record is available. This does not mean all forms are equivalent.

sleep: 3 g before bed; form not reported.

Mechanisms

Mechanistic plausibility is context, not proof that a clinical outcome improves.

No structured mechanism is recorded.

⚠ Safety in context

No interaction record is modeled for this intervention. This is an unknown coverage state, not evidence that no interaction exists.

Products and verification

No product label snapshot is mapped in this released catalog. Ingredient evidence does not establish any bottle’s identity, potency, purity, availability, or value.

Evidence by outcome

sleepgrade Clow certainty— small trials suggest improved subjective sleep quality and reduced next-day fatigue

Grade history

2026-07-16C → CCorrection by Claude (gold-standard provenance sweep): live Postgres source drift replaced with the verified seed source set [pmid-22293292] details →

Re-review cadence: every 6 months (Grade C+) · next scheduled by 2027-01-16 · methodology v1.

By outcome — the money pages

Glycine for sleep — Grade C, low certainty

Compare

Is Glycine hype?

sources: PMID:22293292

Cite this page

Citation is encouraged. The proposed reuse license is CC-BY-4.0; status: pending-governance-ratification.

Plain-text citation

Substrate. Glycine: what the evidence actually shows. https://evidencebased.info/interventions/glycine. Updated 2026-07-16.

BibTeX

@misc{substrate_interventionsglycine,
  author = {Substrate editorial},
  title  = {Glycine: what the evidence actually shows},
  year   = {2026},
  url    = {https://evidencebased.info/interventions/glycine},
  note   = {evidencebased.info}
}