Melatonin vs Valerian

for sleep

Stronger evidence: Melatonin

Stronger effect: Melatonin

Safety: Melatonin carries a uncertain interaction; Valerian has none recorded.

For sleep, Melatonin has the stronger evidence grade.

grade B moderate certainty

reduces time to fall asleep; best for circadian timing

0.5–3 mg

grade C low certainty

small, inconsistent improvements in subjective sleep quality; trials are low-quality

300–600 mg, adults with insomnia

sources: PMID:00000006 · PMID:10000001