Creatine for mood: C → C
Source correction by Claude (b2 garbage-source correction): replaced an off-topic search-fallback source (published before the pump's topicality gate existed) with a real, on-topic paper (PMID 39553021, "Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions."). Verdict/grade unchanged; only the provenance was wrong.
What triggered this change
Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions.. Read: Substrate breakdown · PubMed.
What we said before vs now
Before
Grade C
After
Grade C
emerging evidence as an adjunct for depressive symptoms; trials small
What this does not change
- Interaction profile for Creatine — unchanged unless there is a separate severity change.
- Dose guidance — unchanged unless the new evidence altered the studied dose range.
- Safety recommendations — unchanged unless a safety event is recorded separately.
Reviewer & methodology
Reviewed and signed by Substrate editorial (Independent research collective) on . Methodology v1.
See also
Cite this page
Reuse under CC-BY 4.0 with attribution to evidencebased.info.
Plain-text citation
Substrate. Creatine for mood: C → C. https://evidencebased.info/changes/2026-07-16-creatine-mood-c-to-c. Updated 2026-07-16.
BibTeX
@misc{substrate_0716creatinemoodctoc,
author = {Substrate editorial},
title = {Creatine for mood: C → C},
year = {2026},
url = {https://evidencebased.info/changes/2026-07-16-creatine-mood-c-to-c},
note = {evidencebased.info}
}