Lion's Mane: what the evidence actually shows

emerging  lion's mane — early hype, thin evidence

Reviewed by Substrate editorial, Independent research collective

Evidence by outcome

cognitiongrade Clow certaintyearly, small studies suggest a modest cognitive effect

People say · Evidence shows

Lion's mane regrows brain cells

aheadlargemechanistic speculation

Grade history

No grade changes yet. Initial grade assigned; re-reviewed on every 6 months (Grade C+). Methodology v1.

Re-review cadence: every 6 months (Grade C+) · methodology v1.

By outcome — the money pages

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Plain-text citation
Substrate. Lion's Mane: what the evidence actually shows. https://evidencebased.info/interventions/lions-mane. Updated 2026.
BibTeX
@misc{substrate_terventionslionsmane,
  author = {Substrate editorial},
  title  = {Lion's Mane: what the evidence actually shows},
  year   = {2026},
  url    = {https://evidencebased.info/interventions/lions-mane},
  note   = {evidencebased.info}
}