Vitamin D: what the evidence actually shows

surging  vitamin D — claims outrun the trial evidence

Reviewed by Substrate editorial, Independent research collective

⚠ Safety in context

Evidence by outcome

bone healthgrade Bmoderate certaintysupports bone density and reduces fracture risk with calcium, mainly in deficiency
moodgrade Clow certaintysmall mood benefit, mostly in people who are deficient
immune functiongrade Clow certaintymodest reduction in acute respiratory infection risk, concentrated in deficient people

People say · Evidence shows

Vitamin D fixes almost everything

aheadlargemarketing claim

Grade history

No grade changes yet. Initial grade assigned; re-reviewed on every 12 months (Grade A/B). Methodology v1.

Re-review cadence: every 12 months (Grade A/B) · methodology v1.

By outcome — the money pages

Compare

More

sources: PMID:20000104 · PMID:20000105

Cite this page

Reuse under CC-BY 4.0 with attribution to evidencebased.info.

Plain-text citation
Substrate. Vitamin D: what the evidence actually shows. https://evidencebased.info/interventions/vitamin-d. Updated 2026.
BibTeX
@misc{substrate_nterventionsvitamind,
  author = {Substrate editorial},
  title  = {Vitamin D: what the evidence actually shows},
  year   = {2026},
  url    = {https://evidencebased.info/interventions/vitamin-d},
  note   = {evidencebased.info}
}