Vitamin C: what the evidence actually shows

debunked  vitamin C for colds — popular belief, evidence says otherwise

Reviewed by Substrate editorial, Independent research collective ·

Evidence by outcome

skingrade Clow certaintytopical better-supported than oral; oral may support collagen synthesis
cold preventionstudied, no effectmoderate certaintyno reduction in cold incidence in the general population
moodstudied, no effectmoderate certaintyNot recommended for unipolar depression

People say · Evidence shows

Vitamin C prevents colds

contradictsextremefolk

What it probably doesn't do

Grade history

Re-review cadence: every 6 months (Grade C+) · next scheduled by · methodology v1.

By outcome — the money pages

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sources: PMID:42095579 · PMID:35311615

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Plain-text citation
Substrate. Vitamin C: what the evidence actually shows. https://evidencebased.info/interventions/vitamin-c. Updated 2026-04-12.
BibTeX
@misc{substrate_nterventionsvitaminc,
  author = {Substrate editorial},
  title  = {Vitamin C: what the evidence actually shows},
  year   = {2026},
  url    = {https://evidencebased.info/interventions/vitamin-c},
  note   = {evidencebased.info}
}