Turmeric vs Omega-3

for mood

Stronger evidence: tie

Stronger effect: Omega-3

Safety: Omega-3 has the more serious interaction profile (moderate vs serious).

For mood, the two are evidence-matched; the difference is in effect and safety.

grade C low certainty

curcumin may reduce depressive symptoms as an adjunct; bioavailability-limited

500–1000 mg curcumin/day, adults with depression

grade C moderate certainty

small benefit for depressive symptoms, clearest with higher-EPA formulations

1–2 g EPA, adults with depression

sources: PMID:42186284 · PMID:20000102