Zinc vs Vitamin D

for mood

Stronger evidence: tie

Stronger effect: tie

Safety: Vitamin D carries a minor interaction; Zinc has none recorded.

For mood, the two are evidence-matched; the difference is in effect and safety.

grade C low certainty

may augment antidepressant response; deficiency-correction likely matters

25 mg/day, adults

grade C low certainty

small mood benefit, mostly in people who are deficient

sources: PMID:42197650 · PMID:00000005