Zinc vs Rhodiola

for mood

Stronger evidence: Zinc

Stronger effect: Zinc

Safety: Rhodiola carries a uncertain interaction; Zinc has none recorded.

For mood, Zinc has the stronger evidence grade.

Zinc

grade C low certainty

may augment antidepressant response; deficiency-correction likely matters

25 mg/day, adults

Rhodiola

studied, no effect moderate certainty

Not recommended for mood disorders

sources: PMID:42197650 · PMID:35311615