Zinc vs Collagen
for skin
Stronger evidence: tie
Stronger effect: tie
Safety: No notable interactions recorded for either.
For skin, the two are evidence-matched; the difference is in effect and safety.
Zinc
grade C low certainty
Acquired zinc deficiency is deeply involved in the development of skin diseases including acquired acrodermatitis enteropathica, necrolytic migratory erythema, alopecia, and delayed wound healing, and mutations or dysregulation in zinc transporters are associated with skin manifestations.
Collagen
grade C low certainty
small improvements in skin elasticity/hydration in industry-funded trials
2.5–10 g/day
sources: PMID:29439479 · PMID:00000028