Turmeric vs N-Acetylcysteine

for mood

Stronger evidence: tie

Stronger effect: Turmeric

Safety: Turmeric carries a moderate interaction; N-Acetylcysteine has none recorded.

For mood, the two are evidence-matched; the difference is in effect and safety.

grade C low certainty

curcumin may reduce depressive symptoms as an adjunct; bioavailability-limited

500–1000 mg curcumin/day, adults with depression

grade C low certainty

preliminary evidence as an adjunct in some psychiatric conditions; not established as a standalone

1200–2400 mg/day, adults

sources: PMID:42186284 · PMID:10000012