Omega-3 vs Creatine

for cognition

Stronger evidence: Creatine

Stronger effect: unknown

Safety: Omega-3 carries a serious interaction; Creatine has none recorded.

For cognition, Creatine has the stronger evidence grade.

Omega-3

not well studied very-low certainty

not adequately studied for cognition in healthy adults

Creatine

grade B moderate certainty

Meta-analysis of 16 RCTs (n≈492 adults): improved memory, attention, and processing speed; no significant effect on overall or executive function.

5 g/day
sources: PMID:39070254