Ashwagandha vs Caffeine

for cognition

Stronger evidence: Caffeine

Stronger effect: Caffeine

Safety: Ashwagandha has the more serious interaction profile (moderate vs minor).

For cognition, Caffeine has the stronger evidence grade.

Ashwagandha

grade C low certainty

preliminary improvements in memory/executive function; small trials

300–600 mg/day, adults

Caffeine

grade A high certainty

reliably improves alertness, reaction time, and vigilance

40–200 mg, adults
sources: PMID:42220661 · PMID:00000020