Probiotics vs Vitamin C

for mood

Stronger evidence: Probiotics

Stronger effect: Probiotics

Safety: No notable interactions recorded for either.

For mood, Probiotics has the stronger evidence grade.

grade C low certainty

small effects on mood/anxiety in some "psychobiotic" trials; strain-specific, heterogeneous

strain-dependent, adults

studied, no effect moderate certainty

Not recommended for unipolar depression

sources: PMID:42221774 · PMID:35311615