Magnesium vs N-Acetylcysteine

for mood

Stronger evidence: N-Acetylcysteine

Stronger effect: N-Acetylcysteine

Safety: Magnesium carries a minor interaction; N-Acetylcysteine has none recorded.

For mood, N-Acetylcysteine has the stronger evidence grade.

studied, no effect moderate certainty

Not recommended for unipolar depression

grade C low certainty

preliminary evidence as an adjunct in some psychiatric conditions; not established as a standalone

1200–2400 mg/day, adults

sources: PMID:35311615 · PMID:10000012