{"claimId":"clm_ec_nac_mood","version":1,"status":"current","verdict":"N-Acetylcysteine for mood: Grade C at low certainty. preliminary evidence as an adjunct in some psychiatric conditions; not established as a standalone","direction":"benefit","magnitude":{"metric":"other","value":null,"unit":"","ci95":null,"humanReadable":"preliminary evidence as an adjunct in some psychiatric conditions; not established as a standalone","baselineAbsoluteRisk":null},"certainty":"low","clinicalMeaning":"small_but_potentially_useful","applicability":{"appliesTo":["adults"],"doesNotApply":["children"],"unknown":["pregnancy"]},"safetyQualifiers":[],"evidenceBundleId":"eb_ec_nac_mood","citations":[{"pmid":"10000012"}],"reviewedBy":{"name":"Substrate editorial","credential":"Independent research collective"},"reviewedAt":"2026-07-14T00:00:00Z","dateModified":"2026-07-14T00:00:00Z","methodologyVersion":"v1","methodologyDoi":"https://doi.org/10.5281/zenodo.21364236","canonicalUrl":"https://evidencebased.info/interventions/nac/mood","attribution":"Substrate (evidencebased.info), claim clm_ec_nac_mood v1, reviewed 2026-07-14","license":"CC-BY-4.0 — attribution with link required"}