{"claimId":"clm_ec_b6-vitd-testosterone","version":1,"status":"current","verdict":"Vitamin D for testosterone / hormone levels: Grade C at low certainty. Meta-analysis in men: vitamin D supplementation may increase TOTAL testosterone, but showed no significant effect on free testosterone, FSH, LH, SHBG, free androgen index or estradiol. The isolated total-testosterone signal is modest and the authors call for further well-designed RCTs.","direction":"benefit","magnitude":{"metric":"other","value":null,"unit":"","ci95":null,"humanReadable":"Meta-analysis in men: vitamin D supplementation may increase TOTAL testosterone, but showed no significant effect on free testosterone, FSH, LH, SHBG, free androgen index or estradiol. The isolated total-testosterone signal is modest and the authors call for further well-designed RCTs.","baselineAbsoluteRisk":null},"certainty":"low","clinicalMeaning":"small_but_potentially_useful","applicability":{"appliesTo":["adult men"],"doesNotApply":["children"],"unknown":["pregnancy"]},"safetyQualifiers":[],"evidenceBundleId":"eb_ec_b6-vitd-testosterone","citations":[{"pmid":"39452471","design":"peer-reviewed"}],"reviewedBy":{"name":"Substrate editorial","credential":"Independent research collective"},"reviewedAt":"2026-07-16T16:23:27.231Z","dateModified":"2026-07-16T16:23:27.231Z","methodologyVersion":"v1","methodologyDoi":"https://doi.org/10.5281/zenodo.21364236","canonicalUrl":"https://evidencebased.info/interventions/vitamin-d/testosterone","attribution":"Substrate (evidencebased.info), claim clm_ec_b6-vitd-testosterone v1, reviewed 2026-07-16","license":"CC-BY-4.0 — attribution with link required"}