{"claimId":"clm_ec_b5-ash-immunity","version":1,"status":"current","verdict":"Ashwagandha for immune function: Grade D at very-low certainty. Review: ashwagandha shows immunomodulatory effects in mechanistic and early studies, but clinical evidence that it meaningfully improves immune outcomes in people is preliminary.","direction":"null","magnitude":{"metric":"other","value":null,"unit":"","ci95":null,"humanReadable":"Review: ashwagandha shows immunomodulatory effects in mechanistic and early studies, but clinical evidence that it meaningfully improves immune outcomes in people is preliminary.","baselineAbsoluteRisk":null},"certainty":"very_low","clinicalMeaning":"trivial","applicability":{"appliesTo":["general adult population"],"doesNotApply":["children"],"unknown":["pregnancy"]},"safetyQualifiers":["moderate_with_ssri"],"evidenceBundleId":"eb_ec_b5-ash-immunity","citations":[{"pmid":"36909188","design":"peer-reviewed"}],"reviewedBy":{"name":"Substrate editorial","credential":"Independent research collective"},"reviewedAt":"2026-07-16T15:25:12.951Z","dateModified":"2026-07-16T15:25:12.951Z","methodologyVersion":"v1","methodologyDoi":"https://doi.org/10.5281/zenodo.21364236","canonicalUrl":"https://evidencebased.info/interventions/ashwagandha/immunity","attribution":"Substrate (evidencebased.info), claim clm_ec_b5-ash-immunity v1, reviewed 2026-07-16","license":"CC-BY-4.0 proposed; reuse license pending governance ratification","dataSource":"live"}