{"claimId":"clm_ec_b11-ginkgo-joints","version":1,"status":"current","verdict":"Ginkgo for joint health: Grade D at very-low certainty. Narrative review: Ginkgo biloba extract (EGb 761) has demonstrated anti-inflammatory, antioxidant, and chondroprotective properties in experimental and preliminary clinical research for knee osteoarthritis, but this is a synthesis of mechanistic and early findings, not a meta-analysis of controlled trial outcomes. Too preliminary for a confident effect estimate.","direction":"null","magnitude":{"metric":"other","value":null,"unit":"","ci95":null,"humanReadable":"Narrative review: Ginkgo biloba extract (EGb 761) has demonstrated anti-inflammatory, antioxidant, and chondroprotective properties in experimental and preliminary clinical research for knee osteoarthritis, but this is a synthesis of mechanistic and early findings, not a meta-analysis of controlled trial outcomes. Too preliminary for a confident effect estimate.","baselineAbsoluteRisk":null},"certainty":"very_low","clinicalMeaning":"trivial","applicability":{"appliesTo":["adults with knee osteoarthritis"],"doesNotApply":["children"],"unknown":["pregnancy"]},"safetyQualifiers":["serious_with_warfarin","moderate_with_ssri"],"evidenceBundleId":"eb_ec_b11-ginkgo-joints","citations":[{"pmid":"41425500","design":"peer-reviewed"}],"reviewedBy":{"name":"Substrate editorial","credential":"Independent research collective"},"reviewedAt":"2026-07-16T16:40:59.784Z","dateModified":"2026-07-16T16:40:59.784Z","methodologyVersion":"v1","methodologyDoi":"https://doi.org/10.5281/zenodo.21364236","canonicalUrl":"https://evidencebased.info/interventions/ginkgo/joints","attribution":"Substrate (evidencebased.info), claim clm_ec_b11-ginkgo-joints v1, reviewed 2026-07-16","license":"CC-BY-4.0 — attribution with link required"}